DMSO (dimethyl sulphoxide) is used in medicine and research primarily as a solvent, penetration enhancer and cryoprotectant. The combination with isotonic saline solution is mainly used in experimental and specialized clinical contexts.

DMSO CAS number: 67-68-5
DMSO PubChem CID: 679
DMSO molecular formula: C₂H₆OS
other names / synonyms: Methylsulfoxide & sulfinylbismethane, methylsulfinylmethane, dimexide and the Latin name Dimethylis sulfoxidum

DMSO 3% in saline solution 10 ml pheur: Brown glass bottle with pipette insert and tamper-evident closure

DMSO 3% in saline solution 50 ml pheur: Brown glass bottle with pipette insert and tamper-evident closure

DMSO 3% in saline solution 100 ml pheur: Brown glass bottle with dropper insert, child safety lock and tamper-evident closure

DMSO 3% in saline solution pheur: 10ml brown glass bottle with pipette insert & 100ml brown glass bottle with dropper insert Child safety lock and tamper-evident closure

Intravesical therapy for interstitial cystitis

This is the only officially approved therapeutic use of DMSO in humans (e.g. RIMSO-50 in some countries).

- DMSO is used as a bladder irrigation (instillation)
- The solution is introduced into the bladder and left there for a short time
- Aim: anti-inflammatory, analgesic and muscle relaxant effect

In some protocols, DMSO is combined with isotonic saline to make the application more comfortable or to dilute other ingredients.

Cryopreservation of blood stem cells

DMSO is used here:

- as a cryoprotectant when freezing the cells
- Later, the cells are returned to the patient

After thawing, the cells are often processed in a physiological electrolyte or saline solution.
However, this is not a therapeutic application of DMSO itself, but a side effect of the preservation process.

DMSO has properties that can be problematic if used incorrectly:

- drastically increases the permeability of the skin and mucous membranes
- Can transport other substances into the body in an uncontrolled manner
- Can irritate tissue (especially at higher concentrations)
- Typical side effect: garlicky smell/taste

This is why DMSO is only used in humans under strictly controlled clinical conditions.

Dimethyl sulfoxide (DMSO) 3% pheur (MSDS)

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